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[Obstructive sleep apnea and central/peripheral chemosensitivity: an essential part of pathophysiological mechanisms]
1Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College Chinese Academy of Medical Sciences, Beijing 100730, China.
Abstract:
Unstable ventilatory control is one of the key pathophysiological mechanisms of obstructive sleep apnea (OSA), and the activity of chemoreceptors is an important part of ventilatory control. Chemosensitivity has a significant impact on the severity and prognosis of OSA, and the incidence of comorbidities. The focus on reducing chemosensitivity can be seen as an emerging theme to promote individualized and precise treatment of OSA. Further exploration of chemosensitivity in OSA will be an emerging direction and a major challenge for current and future research in the field of sleep.
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