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Updated: Jul 9, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
A Fluid-Solid-Growth Solver for Cardiovascular Modeling
Erica L Schwarz1, Martin R Pfaller2, Jason M Szafron2
1Department of Bioengineering, Stanford Univeristy, Stanford, CA 94306, USA.
Abstract:
We implement full, three-dimensional constrained mixture theory for vascular growth and remodeling into a finite element fluid-structure interaction (FSI) solver. The resulting "fluid-solid-growth" (FSG) solver allows long term, patient-specific predictions of changing hemodynamics, vessel wall morphology, tissue composition, and material properties. This extension from short term (FSI) to long term (FSG) simulations increases clinical relevance by enabling mechanobioloigcally-dependent studies of disease progression in complex domains.
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