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Sex differences in brain transcriptomes of juvenile Cynomolgus macaques
Nadia Kabbej1, Frederick J Ashby1, Alberto Riva1
1University of Florida.
Research Square
|December 4, 2023
Summary
This study reveals significant sex-based differences in brain gene expression in young macaques. These findings may help explain health disparities between males and females in humans.
Area of Science:
- Neuroscience
- Genomics
- Primatology
Background:
- Limited research exists on sex-based differences in brain gene expression.
- Investigating these differences in non-human primates offers insights into human biology.
Conclusions:
- Findings offer potential explanations for sex-based differences in susceptibility to diseases like COVID-19 and variations in mental health.
- This research provides crucial pre-pubertal data on sex differences in primate brain transcriptomics, informing human health disparity research.
