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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal
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Multi-Scale Geometric Network Analysis Identifies Melanoma Immunotherapy Response Gene Modules.

Kevin A Murgas1, Rena Elkin2, Nadeem Riaz3

  • 1Department of Biomedical Informatics, Stony Brook University, Stony Brook, NY, USA.

Biorxiv : the Preprint Server for Biology
|December 4, 2023
PubMed
Summary
This summary is machine-generated.

Researchers used network analysis to understand melanoma

Area of Science:

  • Oncology

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  • Computational Biology
  • Immunotherapy

    • Background:

    • Melanoma's molecular response to immunotherapy is not fully understood.
    • Identifying molecular markers for treatment response is crucial.

    Conclusions:

    • Dynamic Ollivier-Ricci curvature is effective for identifying functionally relevant gene modules in cancer.
    • The NFKB pathway module shows potential as a biomarker for immunotherapy response in melanoma.