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Cisplatin nephrotoxicity: symptomatic hypomagnesemia and renal failure
The International Journal of Pediatric Nephrology
|July 1, 1986
Summary
High-dose Cisplatin can cause acute renal failure and severe electrolyte disturbances like hypomagnesemia. Prompt magnesium administration may correct these issues, but renal failure can persist despite treatment.
Area of Science:
- Oncology
- Nephrology
- Clinical Pharmacology
Background:
- Cisplatin is a widely used chemotherapy agent for solid tumors.
- Nephrotoxicity is a known side effect of Cisplatin treatment.
- Electrolyte imbalances can occur during Cisplatin therapy.