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Updated: Jul 9, 2025

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Unusual Diffuse and Heterogeneous FDG Uptake in Appendicular Bone Marrow Space in a Patient with Acute Lymphoblastic
1Department of Nuclear Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si, Republic of Korea.
Abstract:
We describe a case of F-18-2-fluoro-2-deoxyglucose (FDG) uptake in the appendicular bones on a positron emission tomography/computed tomography (PET/CT) scan in a 20-year-old woman with a diagnosis of acute lymphoblastic leukemia. An FDG PET/CT was performed on this patient because of fever of unknown origin, revealing diffuse and heterogeneous FDG uptake in the bone marrow space of both humeri, femurs, and tibiae. The patient underwent magnetic resonance imaging, which demonstrated bone infarction with heterogeneous high, intermediate, and dark signal intensities on T1- and T2-weighted images in the same areas.
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