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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Access to 5-Methyl-5H-naphtho[2,3-c]carbazole-8,13-dione Derivatives via Copper-Catalyzed Intramolecular
Hong Xu1,2, Bei Wang3, Fu-Yu Li1,2
1Asymmetric Synthesis and Chiraltechnology Key Laboratory of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, P. R. China.
Abstract:
Carbazole-fused quinones are important compounds for their potential pharmacological activities and photophysical properties. Here, a novel copper-catalyzed intramolecular isomerization process to access a new class of naphtho[2,3-c]carbazole-8,13-dione derivatives via a furan isomerization/γ-H elimination and β-C elimination/6π-electrocyclization/aromatization cascade is reported. Furthermore, the preliminary photophysical properties of the functional 5-methyl-5H-naphtho[2,3-c]carbazole-8,13-dione derivatives have been studied.
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