Cardiovascular-kidney-metabolic syndrome: A step toward multidisciplinary and inclusive care

Area of Science:

• Cardiology
• Nephrology
• Metabolic Health

Background:

• The American Heart Association (AHA) recently defined Cardiovascular-Kidney-Metabolic (CKM) syndrome.
• CKM syndrome encompasses conditions related to dysfunctional or excess adiposity.
• This syndrome is associated with adverse cardiovascular outcomes.

Purpose of the Study:

• To introduce and explain the newly defined Cardiovascular-Kidney-Metabolic (CKM) syndrome.
• To highlight the significance of the AHA's Presidential Advisory report on CKM syndrome.
• To underscore the potential impact of implementing AHA guidelines on population health.

Main Methods:

• Review of the AHA Presidential Advisory report.
• Analysis of the definition and scope of CKM syndrome.
• Evaluation of the proposed implementation strategies for AHA guidelines.

Main Results:

• CKM syndrome is presented as a spectrum of pathology.
• Dysfunctional or excess adiposity is identified as a key factor.
• Adverse cardiovascular outcomes are a direct consequence of CKM syndrome.

Conclusions:

• The AHA's definition of CKM syndrome provides a framework for understanding related conditions.
• Implementing AHA guidelines offers a pathway to improve population-wide CKM health.
• Addressing adiposity is crucial for managing and preventing CKM syndrome and its cardiovascular consequences.