Highly sensitive and selective off-on fluorescent platform for tricresyl phosphate flame retardant based on twisted...

Tricresyl phosphate (TCP), a typical organic phosphorus flame retardant (OPFR), is an emerging pollutant that causes great concern in recent years due to its high neurotoxicity and reproductive toxicity, etc. Conventional analysis methods for TCP such as gas chromatography and liquid chromatography-tandem mass spectrometry exhibit high sensitivity and accuracy. However, these techniques generally suffer from certain limitations, such as high cost, bulky equipment, time-consuming and operator-dependent properties. Therefore, the establishment of fast and efficient analytical methods for TCP still remains a great challenge.

A "turn on" fluorescence sensing strategy for the efficient detection of TCP was established, based on a unique molecular rotor probe of 9-(2,2-dicyanovinyl)-julolidine (DCVJ). The introduction of TCP led to a significant enhancement of the fluorescence intensity of DCVJ. The results show that twisted intramolecular charge transfer (TICT) process might play an important role for this enhancement of fluorescence response via dynamic light scattering measurements and fluorescence lifetime analysis. Further investigations demonstrate that the hydrophobic interaction and conjugation effect between DCVJ and TCP constrain the molecular rotation and vibration of DCVJ, thereby regulating the TICT process, which contribute to this intriguing "turn on" behavior. In view of this, a new sensing platform with excellent performance for TCP was established, which offers quick response time, high selectivity, wide linear range (20-1200 ng mL^-1, 1600-8000 ng mL^-1), and low detection limit (4.82 ng mL^-1).

The established new sensing platform for TCP demonstrates the advantages of simplicity, high efficiency, excellent sensitivity and selectivity. The obtained results are also superior to some other previously reported fluorescence methods. This work opens up a new perspective for the efficient detection of emerging OPFRs pollutants.