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Unveiling strain-level dynamics in probiotic activity
Jiang Chang1, Yuwei Wu1, Hao Wu2
1State Key Laboratory of Genetic Engineering, Fudan Microbiome Center, School of Life Sciences, and Human Phenome Institute, Fudan University, Shanghai 201203, China.
Trends in Microbiology
|December 6, 2023
Abstract:
Divergent gene content among distinct probiotic strains contributes to varied or conflicting clinical efficacies. Zhang et al. unveils a novel bacterial gene signature, particularly the abfA gene cluster, offering a promising avenue for screening probiotics and advancing our understanding of strain-level activities in the context of gastrointestinal health.
