Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Colloidal precipitates01:09

Colloidal precipitates

593
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
593
Coagulation01:06

Coagulation

307
Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
307
Ion Exchange01:17

Ion Exchange

594
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
594

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering the Self-Assembly of Bacterial Microcompartment Shell Proteins via Charged Mutations.

ACS nano·2026
Same author

Solvent-Dependent Mechanical Response of De Novo Helix Repeat Proteins.

The journal of physical chemistry. B·2026
Same author

Mechanophore cross-linking enhances ballistic energy dissipation of polymers.

Nature·2026
Same author

Role of Polymer-Protein Interactions in the Dynamics of Polymer-Integrated Protein Crystals.

Journal of the American Chemical Society·2026
Same author

Electrostatically driven pattern formation in mixed charged-neutral multicomponent elastic membranes.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Self-oscillating synchronematic colloids.

Nature communications·2026

Related Experiment Video

Updated: Jul 9, 2025

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.2K

Induced phase transformation in ionizable colloidal nanoparticles.

Leticia López-Flores1, Monica Olvera de la Cruz2,3,4

  • 1Department of Materials Science and Engineering, Northwestern University, Evanston, IL, 60208, USA.

The European Physical Journal. E, Soft Matter
|December 7, 2023
PubMed
Summary
This summary is machine-generated.

Particle charge, regulated by pH, influences colloidal systems. Increased pH leads to charge polydispersity, causing transitions from ordered to disordered particle arrangements, forming amorphous solids.

More Related Videos

Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids
07:14

Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids

Published on: August 23, 2018

9.1K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

9.8K

Related Experiment Videos

Last Updated: Jul 9, 2025

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.2K
Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids
07:14

Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids

Published on: August 23, 2018

9.1K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

9.8K

Area of Science:

  • Colloid Science
  • Physical Chemistry
  • Computational Physics

Background:

  • Acid-base equilibria critically affect particle functionality and behavior through ionization of functional groups, leading to charge exchange.
  • Controlling particle interactions and ionization requires tuning pH and salt concentration, but modeling these effects, especially charge regulation and cooperative phenomena in colloidal suspensions, remains challenging.
  • Coulombic interactions and charge regulation are difficult to incorporate into theoretical and simulation approaches for ionizable colloidal systems.

Purpose of the Study:

  • To analyze the behavior of ionizable colloidal particles in suspension under varying pH conditions.
  • To investigate the impact of charge regulation on particle arrangement and phase transitions.
  • To derive a phase diagram for the colloidal system as a function of pH.

Main Methods:

  • Utilized molecular dynamics (MD) simulations to study the suspension of ionizable colloidal particles.
  • Employed Monte Carlo simulations for charge regulation (MC-CR) to model the ionization processes.
  • Derived a phase diagram by analyzing simulation results across a range of pH values.

Main Results:

  • Observed a transition in particle arrangement from face-centered cubic (FCC) packing to a disordered state as pH increased.
  • Attributed these structural transitions to an increasing degree of charge polydispersity with rising pH.
  • Demonstrated that charge regulation can induce amorphous solid formation in colloidal systems at sufficiently high mean nanoparticle charge.

Conclusions:

  • Charge regulation significantly influences the macroscopic behavior and phase behavior of ionizable colloidal suspensions.
  • The study provides a framework for understanding and predicting colloidal phase transitions driven by pH-dependent charge variations.
  • Charge regulation is identified as a key mechanism leading to the formation of amorphous solids in charged colloidal systems.