Related Experiment Video
Updated: Jul 9, 2025
07:21
Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
Published on: June 16, 2023
956
[The FORTA (Fit fOR The Aged) List]
Farhad Pazan1, Martin Wehling2
1Ehemals Institut für Klinische Pharmakologie, Medizinische Fakultät Mannheim, Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
Innere Medizin (Heidelberg, Germany)
|December 8, 2023
Summary
The Fit fOR The Aged (FORTA) list significantly improved medication treatment and clinical outcomes like adverse drug events and falls in older patients. This patient-focused approach optimizes prescribing for the elderly.
Area of Science:
- Gerontology and Geriatric Medicine
- Clinical Pharmacology
- Evidence-Based Medicine
Context:
- Polypharmacy and multimorbidity are prevalent in the elderly, with limited drug efficacy and safety data.
- Current guidelines can lead to inappropriate prescribing and drug-related problems in older adults.
Purpose:
- To evaluate the clinical utility of the Fit fOR The Aged (FORTA) list for optimizing medication in older patients.
- To assess the impact of the FORTA list on medication treatment and clinical outcomes.
Summary:
- The most recent FORTA list (2022) includes 299 drugs for 30 age-related indications.
- The VALFORTA study demonstrated that using the FORTA list significantly improved medication treatment.
- The FORTA intervention led to clinically relevant improvements in adverse drug events, activities of daily living, and falls.
Impact:
- Recommends the use of the FORTA list for medication optimization in older patients.
- Highlights the importance of individualized needs analysis (diagnoses, severity, life expectancy, functional status, patient wishes) for FORTA application.
Related Concept Videos
01:26Aging
54
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
54
01:19The Effect of Aging on Tissues
2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
01:19Restorative Care
2.0K
Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
2.0K
01:21Fatigue
185
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
185
01:25Continuing Care
1.5K
Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
1.5K
01:09Changes in the Appendicular Skeleton with Age
2.0K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
2.0K