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Sleep in pediatric neuromuscular disorders

John E Pascoe1, Alexander Zygmunt2, Zarmina Ehsan3

  • 1Division of Pulmonary and Sleep Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Seminars in Pediatric Neurology
|December 8, 2023
PubMed

Insights

Sleep disordered breathing (SDB) affects many children with neuromuscular disorders (NMD). Early diagnosis and treatment, often with ventilation, are crucial to prevent serious health issues.

Area of Science:

  • Pediatric Pulmonology
  • Neurology
  • Sleep Medicine

Background:

  • Sleep disordered breathing (SDB) is common in children with neuromuscular disorders (NMD).
  • Respiratory muscle weakness, altered respiratory drive, and scoliosis exacerbate sleep stress in this population.
  • Untreated SDB can lead to cardiovascular, metabolic, and neurocognitive complications.

Conclusions:

  • Clinicians should maintain a high suspicion for SDB in children with NMD.
  • Individualized assessment is necessary due to varied muscle group involvement.
  • Prompt diagnosis and management of SDB are vital for improving outcomes in pediatric NMD.

Keywords:
HypoventilationNeuromuscular disordersNon-invasive ventilationSleep disordered breathing

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