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Extracorporeal Membrane Oxygenation (ECMO)-Associated Coagulopathy in Adults
Frantzeska Frantzeskaki1, Dimitrios Konstantonis1, Michail Rizos1
12nd Critical Care Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 157 72 Athens, Greece.
Abstract:
Extracorporeal membrane oxygenation (ECMO) is used for the management of severe respiratory and cardiac failure and as a bridge to achieve definite treatment or transplantation. ECMO-associated coagulopathy (EAC) is a frequent complication leading to high rates of thrombosis or severe haemorrhage, contributing to morbidity and mortality among patients. Understanding the pathophysiology of EAC is substantial for effectively managing patients on ECMO. We analyse the underlying mechanism of EAC and discuss the monitoring of the coagulation profile, combining the viscoelastic point-of-care assays with the conventional coagulation laboratory tests.
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