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Updated: Jul 9, 2025
Assessing Functional Performance in the Mdx Mouse Model
Published on: March 27, 2014
ASSESSMENT OF LABORATORY ANIMAL FUNCTIONAL STATUS: MODERN METHODOLOGICAL APPROACHES FOR CONDUCTING BIOMEDICAL
Larysa Ya Fedoniuk1, Yulia V Lomakina2, Yaroslav O Bilyk1
1I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE.
Objective:
Aim: to outline modern scientific approaches for evaluating the functional condition of small laboratory animals in experimental research.
Patients And Methods:
Materials and Methods: Scientific publications on the rules of using laboratory animals in scientific experiments, testing, educational process have been studied. The bioethical norms and principles of animal care and use of material for medical, veterinary and biological profiles were also studied, for example modern methodological approaches for conducting biomedical research, since it is the responsibility of the scientist to achieve reproducible research results using the minimum number of laboratory animals.
Conclusion:
Conclusions: The main conditions for their implementation and effectiveness include: adherence to the "Ethical Code" published by the International Council for Medical Scientific Organizations in the early 1980s, the principles of the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (Strasbourg, 18 March 1986), and Directive 2010/63/EU adopted on 22 September 2010; the use of advanced and modern diagnostic equipment that enables low-invasive yet highly informative research on small laboratory animals; conducting comprehensive, multi-level studies on an optimal number of animals in laboratories that meet international standards.
