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[Prospect of novel therapies in immune-mediated neuropathies]

Motoi Kuwahara1

  • 1Department of Neurology, Kindai University Faculty of Medicine.

Rinsho Shinkeigaku = Clinical Neurology
|December 10, 2023
PubMed

The efficacy of immunotherapies such as steroids, plasmapheresis, and intravenous immunoglobulin have been proven in various immune-mediated neuropathies. However, these treatments sometimes lack the efficacy in a part of patients with the immune-mediated neuropathies. In addition, anti-myelin associated glycoprotein (MAG) neuropathy is usually refractory to the treatments. Recently, novel therapies targeting a molecule which are associated with pathogenesis of immune-mediated diseases, have been developed. These molecularly targeted therapies are notable in immune-mediated neuropathies as novel drug candidates. In the present article, current treatments and future prospect of novel therapies in immune-mediated neuropathies will be reviewed.

Keywords:
Guillain–Barré syndromeanti-MAG neuropathychronic inflammatory demyelinating polyradiculoneuropathymultifocal motor neuropathynovel therapies

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