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Updated: Jul 8, 2025

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Prostate Cancer in the Caribbean
Nuneaton S Ramesar1, Amalia Hosein2, Kristy Samaroo2
1General Practice/Public Health/Occupational Health, The University of Trinidad and Tobago, Port of Spain, TTO.
Prostate cancer (PC) research in the Caribbean reveals significant disparities. Lower-resource nations face worse PC outcomes, highlighting an urgent need for improved surveillance and standardized treatments across the region.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- Prostate cancer (PC) is a leading cause of cancer death globally.
- The Caribbean region exhibits higher PC mortality rates and variable incidence compared to many developed nations.
- Limited PC research in the Caribbean creates a significant literature gap.
Purpose of the Study:
- To conduct a comprehensive literature review on the prostate cancer (PC) situation in the Caribbean.
- To identify research gaps and areas requiring further investigation.
- To provide foundational data for PC healthcare planning and research in the region.
Main Methods:
- Systematic literature review of studies on prostate cancer (PC) in the Caribbean population from 1958 to 2023.
- Searched PubMed, Scopus, and ScienceDirect databases using keywords 'Prostate Cancer and Caribbean'.
- Information categorized by Caribbean country and seven key themes: incidence/mortality, demographics, clinicopathology, genetics, non-genetic risks, diagnosis/treatment, and PC control.
Main Results:
- Countries with fewer resources experience a disproportionately higher burden of severe prostate cancer (PC) and poorer outcomes.
- Territories with established national cancer registries demonstrate more effective PC management strategies.
- Significant variations in PC incidence and mortality exist among Caribbean nations.
Conclusions:
- This review highlights critical disparities in prostate cancer (PC) burden and outcomes within the Caribbean.
- Findings support the need for targeted research, improved surveillance, and standardized treatment protocols.
- Further epidemiological analysis is recommended to deepen understanding and enhance PC healthcare strategies in the Caribbean.
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