Fingertip Strain Plethysmography: Representation of Pulse Information based on Vascular Vibration

This study presents fingertip strain plethysmography (SPG) as a visual trace of cardiac cycles in peripheral vessels. The setup includes a small, sensitive MEMS strain sensor attached to the fingertip to capture the pulsatile vibrations corresponding to cardiac cycles. SPG is evaluated on 10 healthy subjects for the estimation of heart rate (HR) and heart rate variability (HRV), as well as heartbeat-derived respiratory rate (RR) which is an HRV parameter. The estimated parameters are compared with a simultaneously-recorded electrocardiogram (ECG) for HR and HRV, and an inertial sensor placed on the chest wall for RR. Bland-Altman analyses suggest small estimation biases of 0.03 beats-per-minute (BPM) and 0.38 ms for HR and HRV respectively, demonstrating excellent agreement between fingertip SPG and ECG. The average estimation accuracies of 99.88% (± 0.04), 96.43% (± 1.44), and 92.64% (± 2.30) for HR, HRV, and RR respectively, prove the reliability of SPG for hemodynamic monitoring.Clinical Relevance- Conventional plethysmography sensors are either cumbersome or susceptible to skin color. This effort is a fundamental step towards the augmentation of conventional methods, thus ensuring stable, clinical-grade hemodynamic monitoring.