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In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
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Changing spectrum of primary pyomyositis in North India

Krishna Divyashree1, Ashok Kumar Pannu2, Atul Saroch2

  • 1Senior Resident, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh, India.

Tropical Doctor
|December 12, 2023
PubMed

Insights

Primary pyomyositis is increasing globally, often caused by community-associated methicillin-resistant Staphylococcus aureus. This infection frequently spreads to the lungs, with mortality linked to high international normalised ratio.

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Microbiology

Background:

  • Primary pyomyositis epidemiology is evolving globally.
  • Understanding its clinical and microbiological spectrum is crucial.

Purpose of the Study:

  • To investigate the clinical and microbiological features of primary pyomyositis.
  • To analyze trends between 2013 and 2021 in India.

Main Methods:

  • Retrospective hospital-based study.
  • Data collected from PGIMER, Chandigarh, India.
  • Analysis of patient demographics, clinical presentation, microbiology, and outcomes.

Main Results:

  • Predisposing conditions like diabetes mellitus and immunosuppression were common.
  • Staphylococcus aureus, including methicillin-resistant strains, was the main pathogen.
  • Two-thirds presented with metastatic infection, often with septic lung emboli.
  • In-hospital mortality was approximately 10%, associated with high international normalised ratio.

Conclusions:

  • Primary pyomyositis is a significant health concern with increasing incidence.
  • Community-associated methicillin-resistant Staphylococcus aureus is a growing threat.
  • Prompt diagnosis and management are essential to improve patient outcomes.
Keywords:
Primary pyomyositisStaphylococcus aureusinfectious myositismethicillin-resistant Staphylococcus aureusseptic lung embolitropical

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