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Pediatric Renal Rickets at a Tertiary Center

Ankur Singh1, - Sucheta2, Rupal Gupta2

  • 1Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh. Correspondence to: Dr Ankur Singh, Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005. pediaankur@gmail.com.

Indian Pediatrics
|December 13, 2023
PubMed
Abstract

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In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
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