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Related Experiment Video

Updated: Jul 8, 2025

Measuring Local Anaphylaxis in Mice

Measuring Local Anaphylaxis in Mice

Published on: October 14, 2014

Occupational anaphylaxis-Data from the anaphylaxis registry.

Margitta Worm¹, Veronika Höfer¹, Sabine Dölle-Bierke¹

¹Division of Allergy and Immunology, Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

|December 14, 2023

Summary

Occupational anaphylaxis is often caused by insect venom, affecting younger individuals compared to non-occupational cases. Foods and drugs are less common triggers, with latex-induced reactions being rare.

Keywords:

drugs food allergy latex occupational anaphylaxis venom

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Published on: September 14, 2018

Area of Science:

Allergy and Immunology
Occupational Health
Epidemiology

Background:

Limited epidemiologic data exists on occupational anaphylaxis.
There is a need for increased knowledge regarding work-related anaphylactic episodes.

Purpose of the Study:

To identify and analyze cases of occupational anaphylaxis.
To investigate the causes, demographics, clinical severity, and management of work-related anaphylaxis.

Main Methods:

Utilized data from the Anaphylaxis Registry.
Identified cases linked to occupational exposure.
Analyzed elicitors, patient demographics, reaction severity, and management strategies.

Main Results:

225 (3.8%) of 5851 registered cases were occupationally related anaphylaxis.
Insects (82.7%), food (12.0%), and drugs (3.6%) were the primary occupational allergens.
Occupational insect venom anaphylaxis occurred in younger individuals (46 vs. 53 years) with a higher incidence of bee stings and venom immunotherapy.

Conclusions:

Venom allergy significantly impacts work-related anaphylaxis.
Foods and drugs are less frequent triggers, and latex-induced occupational anaphylaxis is uncommon.
Further research is required to identify risk factors for occupational anaphylaxis.