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Related Concept Videos

Patterns of Fever01:26

Patterns of Fever

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Before understanding the types and patterns of fever, it is essential to know its phases.
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Acute Pharyngitis01:30

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Increased Body Temperature01:25

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
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Related Experiment Video

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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

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Typhoid fever.

James E Meiring1,2, Farhana Khanam3, Buddha Basnyat4

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This summary is machine-generated.

Typhoid fever, a bloodstream infection caused by Salmonella Typhi, significantly impacts Africa and Asia. Recent advancements focus on understanding its burden, pathogenesis, and developing effective vaccines.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Global Health

Background:

  • Typhoid fever is an invasive bacterial disease caused by Salmonella Typhi, transmitted via the fecal-oral route.
  • It disproportionately affects young individuals in Africa and Asia, leading to a high disease burden.
  • Current diagnosis relies on blood culture, but novel diagnostic methods are under development.

Purpose of the Study:

  • To provide a timely update on the progress made since 2017 in understanding and combating typhoid fever.
  • To highlight advancements in defining the global burden of typhoid fever and antimicrobial resistance.
  • To discuss progress in disease pathogenesis, immunological protection, and vaccine development.

Main Methods:

  • Review of recent scientific literature and clinical trial data.
  • Analysis of global disease burden and antimicrobial resistance patterns.
  • Controlled human infection studies to understand pathogenesis and immunological responses.

Main Results:

  • Significant progress in defining the global burden of typhoid fever and antimicrobial resistance.
  • Improved understanding of disease pathogenesis and immunological protection.
  • Advancement of effective vaccination programs through multipartner collaboration and clinical trials.

Conclusions:

  • Substantial progress has been achieved in typhoid fever research and control efforts since 2017.
  • Continued collaboration and targeted research are crucial for future priorities in global typhoid control.
  • Novel diagnostics and effective vaccination strategies are key to reducing the burden of this invasive bacterial disease.