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Updated: Jul 8, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Pd(II)-Catalyzed tandem selective dehydrogenative [4+2] annulation of 2-methyl-1,3-cycloalkanediones with olefins
Xu Zhang1, Di Wang1, Mengfan Chang1
1College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China. zhangxuedu@126.com.
Abstract:
A practical and effective palladium-catalyzed selective dehydrogenative [4+2] annulation of 2-methyl-1,3-cycloalkanediones with olefins was reported. The active 2-methylene-1,3-cycloalkanedione was in situ generated via Pd-catalyzed enolate oxidation processes, and it subsequently reacted with a wide variety of olefins to afford various polysubstituted dihydropyran derivatives in good to excellent yields.
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