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Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
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Consensus conference statement on fluorescence-guided surgery (FGS) ESSO course on fluorescence-guided surgery.

M A van Dam1, O D Bijlstra2, R A Faber1

  • 1Department of Surgery, Leiden University Medical Center, the Netherlands.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|December 17, 2023
PubMed
Summary
This summary is machine-generated.

Fluorescence-guided surgery (FGS) is established for tissue perfusion and vital structure imaging. Further research is needed for tumor imaging due to a lack of consensus among experts.

Keywords:
Conference consensus statementFluorescenceFluorescence-guided surgeryImagingIndocyanine green

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Area of Science:

  • Surgical Innovation
  • Medical Imaging Techniques
  • Evidence-Based Medicine

Background:

  • Fluorescence-guided surgery (FGS) shows promise across surgical specialties but lacks evidence for standard-of-care adoption.
  • A consensus statement was developed to address the current applications of FGS.

Purpose of the Study:

  • To establish a consensus on the current applications of fluorescence-guided surgery (FGS).
  • To evaluate expert agreement on FGS utility across different surgical domains.

Main Methods:

  • An international FGS course participants anonymously voted on 36 statements.
  • Consensus required ≥70% agreement with ≥80% participation.
  • Voting was stratified by user experience across five applicability domains.

Main Results:

  • Consensus was reached on 17 out of 36 statements (45%).
  • Highest agreement was for tissue perfusion (71%) and biliary/urinary tract visualization (67%).
  • Lowest agreement (0%) was observed for tumor imaging.

Conclusions:

  • FGS is established for tissue perfusion and vital structure imaging.
  • Lymphatic imaging is evolving; tumor imaging shows early promise but requires more research.
  • Quantification and targeted imaging are advancing, necessitating further clinical validation.