Related Experiment Video
Updated: Jul 8, 2025
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Characteristics of vitiligo patients with versus without associated autoimmune thyroid disease
Ze Ma1, Peng Cao2, Menghan Cai1
1Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Background:
Clinical data are limited in patients with vitiligo with or without autoimmune thyroid disease.
Objectives:
The objective of the study was to investigate the clinical features and basic data of patients with vitiligo, especially those with autoimmune thyroid disease.
Methods:
The study was a single-center retrospective study. A total of 1305 patients with vitiligo from June 2018 to May 2023 were included, and the clinical characteristics and basic information of the patients were recorded in detail.
Results:
We identified an association between sex (odds ratio [OR]: 2.380; 95% confidence interval [CI]: 1.772-1.198), vitiligo duration (OR: 1.449; 95% CI: 1.076-1.952), skin involvement exceeding 5% of the body surface area (OR: 3.764; 95% CI: 2.134-6.640), negative emotions (OR: 3.076; 95% CI: 2.292-4.127), vitiligo type (OR: 1.974; 95% CI: 1.096-3.555), family history of AITD (OR: 4.979; 95% CI: 2.687-9.225), and family history of AD (OR: 2.418; 95% CI: 1.410-4.146) and patients with vitiligo.
Conclusions:
For patients with statistically significant associated risk factors, differential diagnosis and early intervention should be performed.
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