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Updated: Jul 8, 2025

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

Microstructural differences in migraine: A diffusion-tensor imaging study.

Dóra Dobos^1,2,3, Gyöngyi Kökönyei^1,2,3,4, Gyula Gyebnár⁵

¹NAP3.0-SE Neuropsychopharmacology Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, Hungary.

Cephalalgia : an International Journal of Headache

|December 19, 2023

Summary

This summary is machine-generated.

Migraine is linked to brain microstructure changes, particularly in visual areas. Longer migraine duration correlates with alterations in brain regions associated with the default mode network.

Keywords:

Migraine default mode network diffusion-tensor imaging microstructural integrity

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Last Updated: Jul 8, 2025

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Area of Science:

Neuroimaging
Neuroscience
Radiology

Background:

Diffusion-tensor imaging (DTI) assesses whole-brain microstructural integrity.
Previous studies on migraine-related microstructural alterations show inconsistent findings.
This study aimed to replicate frequent DTI findings in migraine and explore correlations with migraine parameters.

Purpose of the Study:

To investigate microstructural brain changes in migraine patients using DTI.
To determine if migraine characteristics (intensity, frequency, duration) correlate with observed microstructural alterations.

Main Methods:

Collected diffusion-weighted MRI data from 37 migraine patients and 40 controls.
Analyzed fractional anisotropy (FA) and mean diffusivity (MD) using voxel-wise analysis in SPM12.
Correlated self-reported migraine parameters with regional FA and MD values.

Main Results:

Migraine patients exhibited reduced FA in occipital regions.
Increased FA was observed in thirteen other brain clusters in migraine patients.
Decreased MD was found in the cerebellum and pons; no increased MD was detected.
Migraine duration positively correlated with FA in the frontal cortex and negatively in the superior parietal lobule.

Conclusions:

Migraine is associated with impaired microstructural integrity in visual brain areas.
Migraine duration correlates with microstructural alterations in default mode network regions.