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[Antigenic structure of strains of Pasteurella multocida]
Veterinarno-Meditsinski Nauki
|January 1, 1986
Summary
This study identified a new Pasteurella multocida strain (547) from pigs, finding its main somatic antigen is 0:6. This research aids in understanding Pasteurella multocida strains and their antigenic properties.
Area of Science:
- Veterinary Microbiology
- Bacteriology
- Immunology
Background:
- Pasteurella multocida is a significant bacterial pathogen causing various infections in animals.
- Accurate strain identification and characterization are crucial for effective disease control and prevention.
Purpose of the Study:
- To serologically and immunologically characterize a novel Pasteurella multocida strain (PM-547) isolated from pigs with acute Pasteurella infection.
- To determine the antigenic formula and identify key somatic and subsidiary antigens of the new strain.
Main Methods:
- Isolation and identification of Pasteurella multocida strain PM-547 from infected pigs.
- Serological and immunological analysis using homologous sera.
- Immunodiffusion tests with heat-resistant, water-soluble antigens.
Main Results:
- Strain PM-547 showed the closest antigenic relationship to strain R-473.
- The main somatic antigen was identified as 0:6, with an antigenic formula of 6:B.
- Subsidiary antigens were identified, differentiating PM-547 from other reference strains (R-473, 1235, 989).
Conclusions:
- The immunodiffusion test using specific sera and heat-stable antigens effectively correlates with established methods for typing Pasteurella multocida strains.
- Characterization of strain PM-547 provides valuable data for understanding Pasteurella multocida epidemiology and developing targeted control strategies.
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