Related Experiment Video
Updated: Jul 8, 2025

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
PRISMA-the 100 most-cited articles on chondrosarcoma recurrence: A bibliometric analysis
Baoquan Xin1,2, Guangjian Bai1,2, Pan Gao2,3
1School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
This study analyzed the top 100 cited articles on chondrosarcoma (CHS) recurrence. Research is citation-rich but focuses on treatments, highlighting a need for mechanistic exploration for future breakthroughs.
Area of Science:
- Orthopedics
- Oncology
- Bibliometrics
Background:
- Chondrosarcoma (CHS) is the most common adult malignant bone tumor and is prone to recurrence.
- Understanding research trends in CHS recurrence is crucial for advancing treatment strategies.
Purpose of the Study:
- To identify and analyze the top 100 most-cited articles on chondrosarcoma recurrence.
- To provide researchers with a concise overview of the field's focus and progress.
Main Methods:
- Bibliometric analysis of 305 articles on CHS recurrence published between 2013 and 2022.
- Selection of the top 100 most-cited articles based on Web of Science data.
- Analysis of publication year, journal, country, institution, and keywords.
Main Results:
- The most cited article received 224 citations.
- Key journals include 'Clinical Orthopaedics Related Research'; leading institutions are Fudan University, University of Texas System, and Royal Orthopaedic Hospital.
- China and the USA are the most represented countries; 2018 was the most productive year.
Conclusions:
- Research on CHS recurrence is highly cited.
- Current research emphasizes treatment over mechanistic understanding.
- Future breakthroughs require deeper exploration of underlying mechanisms.
Related Concept Videos
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Abnormal Proliferation
Cancer Survival Analysis
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Targeted Cancer Therapies
There are several types of targeted therapies against...

