Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Connective Tissue Cell Types

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

EVALUATION OF THE RADIOISOTOPIC SYNOVECTOMY PROTOCOL IN PATIENTS WITH HEMOPHILIA.

Acta ortopedica brasileira·2026

Same author

New Treatment in Haemophilia: Challenges, Controversies and Uncertainties.

Haemophilia : the official journal of the World Federation of Hemophilia·2026

Same author

Plain Language Summary on Safety and Efficacy of Damoctocog Alfa Pegol in Previously Treated Children Aged 7 to < 12 Years With Severe Haemophilia A in the Phase 3, Open Label Alfa-PROTECT Main Study.

European journal of haematology·2026

Same author

Safety and Efficacy of Damoctocog Alfa Pegol in Previously Treated Children Aged 7 to < 12 Years With Severe Haemophilia A in the Phase 3, Open Label Alfa-PROTECT Main Study.

European journal of haematology·2026

Same author

Current Concepts in Viscosupplementation: New Classification System and Emerging Frontiers.

Bioengineering (Basel, Switzerland)·2025

Same author

ASSESSMENT OF ISOMETRIC AND ISOKINETIC ANKLE STRENGTH MEASURES: A PILOT STUDY.

Acta ortopedica brasileira·2025

Search research articles

Related Experiment Video

Updated: Jun 21, 2026

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis

Published on: January 4, 2019

EFFECTIVENESS OF VISCOSUPPLEMENTATION IN THE TREATMENT OF HEMOPHILIC ARTHROPATHY: A SYSTEMATIC REVIEW.

Samilly Conceição Maia Martins¹, Erion DE Andrade², Mayara Branco E Silva¹

¹Universidade Estadual de Campinas, Faculdade de Ciencias Medicas, Departamento de Ortopedia e Traumatologia, Campinas, SP, Brazil.

Acta Ortopedica Brasileira

|December 20, 2023

Summary

Viscosupplementation effectively reduces pain and improves joint function and quality of life in patients with hemophilic arthropathy (HA). This treatment appears safe, offering a promising option for managing this condition.

Keywords:

Arthropathy Hemarthrosis Hemophilia Hyaluronic Acid Pain Management Viscosupplementation

More Related Videos

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Published on: September 29, 2018

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

Related Experiment Videos

Last Updated: Jun 21, 2026

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis

Published on: January 4, 2019

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Published on: September 29, 2018

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

Area of Science:

Orthopedics
Hematology
Rheumatology

Background:

Hemophilic arthropathy (HA) significantly impacts patients' quality of life, causing pain and functional limitations.
Current treatment options for HA may not fully address pain and mobility issues.

Purpose of the Study:

To evaluate the efficacy of viscosupplementation in managing pain, limb functionality, and quality of life in patients with hemophilic arthropathy.

Main Methods:

A systematic literature review was conducted following PRISMA guidelines.
Searches were performed across multiple databases (PubMed, Cochrane, EMBASE, etc.) using specific keywords related to hemophilia and viscosupplementation.
Data from 10 selected articles, encompassing 297 joints in 177 patients, were analyzed.

Main Results:

Viscosupplementation demonstrated positive outcomes in alleviating pain associated with hemophilic arthropathy.
Improvements in functional capacity and overall quality of life were observed in patients receiving treatment.
No significant adverse effects were reported, indicating a favorable safety profile.

Conclusions:

Despite limited existing evidence, viscosupplementation, particularly with hyaluronic acid, shows potential as an effective and safe therapeutic strategy for hemophilic arthropathy.
Further research is warranted to solidify the role of viscosupplementation in HA management.