The interventions to improve medication adherence in coronary heart disease patient: A systematic review

Amanda Marselin1,2, Lia Amalia1, Lucia K Dinarti3

  • 1School of Pharmacy, Institut Teknologi Bandung, Indonesia.

Insights

Improving medication adherence in coronary heart disease (CHD) patients is crucial. Interventions, especially m-health, effectively enhance adherence, but long-term strategies require attention.

Area of Science:

  • Cardiology
  • Health Informatics
  • Public Health

Background:

  • Medication adherence significantly impacts clinical outcomes and quality of life for patients with coronary heart disease (CHD).
  • Non-adherence leads to suboptimal treatment results and increased healthcare costs.
  • Effective interventions are needed to improve medication adherence in CHD patients.

Purpose of the Study:

  • To systematically review and describe the effectiveness of interventions aimed at improving medication adherence in CHD patients.
  • To identify common intervention strategies and their impact on adherence rates.

Main Methods:

  • A systematic review was conducted using Scopus and PubMed databases.
  • PRISMA guidelines were followed for article selection, with 31 articles included from an initial 788.
  • The primary outcome measured was medication adherence in CHD patients.

Main Results:

  • Mobile health (m-health) interventions, including text messages and smartphone applications, were most common (15 articles) and effectively improved adherence.
  • Non-m-health interventions such as self-efficacy programs, health worker education, and clinical pharmacy services also showed positive effects.
  • Some studies indicated a decrease in adherence over long follow-up periods, highlighting the need for sustained management.

Conclusions:

  • Various programs, including m-health and non-m-health approaches, can enhance medication adherence in CHD patients.
  • Modifying interventions to improve communication, motivation, and knowledge is key to sustained adherence.
  • Long-term adherence management requires ongoing attention from healthcare professionals.
Abstract

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