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Non‑functional paraganglioma: A case report
Zheng Liu1, Yang Zhang1, Xingyuan Zhang1
1Department of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, Shandong 256603, P.R. China.
Experimental and Therapeutic Medicine
|December 21, 2023
Summary
This study details a rare case of non-functional paraganglioma (PGL) in a 64-year-old female. Surgical resection led to a successful recovery, highlighting PGL diagnosis and treatment.
Area of Science:
- Endocrinology
- Oncology
- Surgical Pathology
Background:
- Paragangliomas (PGL) are rare neuroendocrine tumors originating from chromaffin cells.
- PGL often presents with hypertension and metabolic abnormalities, but non-functional variants lack typical symptoms.
- Accurate diagnosis and treatment of PGL are crucial for patient outcomes.
Observation:
- A 64-year-old female presented with epigastric malaise, diagnosed with a large retroperitoneal mass.
- Contrast-enhanced CT revealed a ~6.5x5.4x6.6 cm lesion anterior to the right kidney with vascularity.
- The patient had no typical symptoms of functional PGL.
Findings:
- The retroperitoneal mass was surgically resected, confirming a diagnosis of paraganglioma.
- Postoperative recovery was uneventful, with the patient discharged in good condition.
- The case underscores the challenges in diagnosing non-functional PGL.
Implications:
- This case highlights the importance of considering PGL in patients with unexplained abdominal masses, even without hormonal symptoms.
- Early surgical intervention for PGL can lead to favorable outcomes.
- Further research into non-functional PGL diagnostics and management is warranted.
