A study of interferences in glucose measurements in blood by hydrogen peroxide based glucose probes

The main blood constituents which could interfere in clinical glucose measurements using a hydrogen peroxide based glucose electrode have been investigated using several different membranes and constant and sweeping potentials. Both diluted and whole undiluted sera were investigated. With a 3500 molecular weight cut-off (MWCO) membrane, acetaminophen, cysteine, and ascorbic acid can interfere. With a 100 MWCO membrane, only acetaminophen interfered.