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A Fiber-Optical Dosimetry Sensor for Gamma-Ray Irradiation Measurement in Biological Applications.
Adel Shaaban Awad Elsharkawi1,2, Huda A Alazab3, Mahmoud Sayed1
1Department of Radiation Engineering, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo 11787, Egypt.
Biosensors
|December 22, 2023
Summary
This study introduces a novel fiber-optical dosimetry sensor (FOD) for precise radiation measurement in biological applications. The new FOD demonstrates superior stability and sensitivity compared to traditional detectors, especially in in vivo animal models.
Area of Science:
- Biomedical Engineering
- Radiation Physics
- Sensor Technology
Background:
- Accurate radiation dosimetry is crucial for medical and industrial applications.
- Existing radiation dosimeters face limitations in tolerance and precision, particularly in biological settings.
- Fiber-optical dosimetry offers a promising alternative for enhanced radiation measurement capabilities.
Purpose of the Study:
- To develop and evaluate a novel two-dimensional (2D) fiber-optical dosimeter (FOD) for radiation measurement.
- To assess the performance of the FOD in biological applications, including in vivo animal models.
- To compare the FOD's stability and sensitivity against standard thermo-luminescence detectors.
Main Methods:
- Fabrication of a 2D array of hollow cylinder-shaped FOD sensors.
- Irradiation of sensors using 137Cs (low doses) and 60Co (high doses) gamma-ray facilities.
- Measurement of sensor response before and after irradiation.
- Implementation of a 2D simulation program for in vivo absorbed dose calculations.
- In vivo testing of FOD sensors transplanted inside animal models.
Main Results:
- The proposed FOD sensors exhibited high stability and sensitivity when subjected to gamma-ray radiation.
- Measurements of FOD sensors transplanted inside animals were successfully performed for the first time.
- The 2D simulation program accurately modeled absorbed dose based on attenuation factors.
- Comparison with thermo-luminescence detectors showed the FOD's superior performance in in vivo tests.
Conclusions:
- The novel 2D fiber-optical dosimeter (FOD) is a stable and sensitive radiation measurement tool.
- The FOD shows significant potential for accurate dosimetry in industrial and medical applications, especially in biological contexts.
- The successful in vivo application marks a significant advancement in radiation detection for biological research.
