The Role of Multimodality Imaging in Patients with Congenital Heart Disease and Infective Endocarditis
Sara Moscatelli1,2, Isabella Leo3,4, Francesco Bianco5
1Inherited Cardiovascular Diseases, Great Ormond Street Hospital, Children NHS Foundation Trust, London WC1N 3JH, UK.
Insights
Diagnosing infective endocarditis (IE) in congenital heart disease (CHD) patients is challenging. Multimodality imaging offers a comprehensive approach to improve diagnostic accuracy and guide treatment for better patient outcomes.
Area of Science:
- Cardiology
- Medical Imaging
- Infectious Diseases
Background:
- Infective endocarditis (IE) poses significant challenges in patients with congenital heart disease (CHD).
- Early and accurate diagnosis of IE in CHD is critical for effective management and improved patient outcomes.
- Multimodality imaging is increasingly recognized as a valuable tool for IE diagnosis in this population.
Purpose of the Study:
- To review the utility of various imaging modalities in diagnosing IE in CHD patients.
- To highlight how multimodality imaging enhances diagnostic accuracy and guides therapeutic strategies.
- To discuss the specific contributions and limitations of each imaging technique.
Main Methods:
- Review of transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE).
- Evaluation of cardiac computed tomography (CCT) and cardiovascular magnetic resonance imaging (CMR).
- Assessment of nuclear imaging modalities for IE detection in CHD.
Main Results:
- Each imaging modality provides unique insights into valvular and intracardiac structures.
- Imaging techniques are crucial for identifying vegetation, abscesses, and complications.
- Multimodality imaging offers a comprehensive view, aiding in timely clinical decisions.
Conclusions:
- Multimodality imaging significantly enhances the diagnosis and management of IE in CHD patients.
- Understanding the strengths and limitations of each technique is vital for optimal application.
- Integrated imaging approaches improve diagnostic confidence and patient care pathways.
Abstract:
Infective endocarditis (IE) represents an important medical challenge, particularly in patients with congenital heart diseases (CHD). Its early and accurate diagnosis is crucial for effective management to improve patient outcomes. Multimodality imaging is emerging as a powerful tool in the diagnosis and management of IE in CHD patients, offering a comprehensive and integrated approach that enhances diagnostic accuracy and guides therapeutic strategies. This review illustrates the utilities of each single multimodality imaging, including transthoracic and transoesophageal echocardiography, cardiac computed tomography (CCT), cardiovascular magnetic resonance imaging (CMR), and nuclear imaging modalities, in the diagnosis of IE in CHD patients. These imaging techniques provide crucial information about valvular and intracardiac structures, vegetation size and location, abscess formation, and associated complications, helping clinicians make timely and informed decisions. However, each one does have limitations that influence its applicability.
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