Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

High-Performance Liquid Chromatography: Elution Process

High-Performance Liquid Chromatography: Elution Process

In High-Performance Liquid Chromatography (HPLC), the elution process is critical to the separation of analytes and the quality of chromatographic results. Elution describes how compounds move through the column and separate based on their interactions with the mobile and stationary phases. This process determines the resolution, peak shape, and retention times in the chromatogram, which are essential for identifying and quantifying components in complex mixtures. Understanding the elution...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Research progress of cuproptosis, ferroptosis, apoptosis, and autophagy in knee osteoarthritis.

Frontiers in cell and developmental biology·2026

Same author

Family Size and Longitudinal Outcomes of a Digital-Human Parenting Intervention in Chinese Preschool Families: Secondary Analysis.

Journal of medical Internet research·2026

Same author

Admission-Based Machine-Learning Models for Predicting Mechanical Ventilation and Mortality in Fibrotic Interstitial Lung Disease: A Multicenter Cohort Study with External Validation.

Balkan medical journal·2026

Same author

Biomechanical evaluation of a fully cortical-threaded screw for modified cortical bone trajectory fixation: Combined experimental and finite element study.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine·2026

Same author

Therapy of allergic rhinitis using ribavirin spray to clear nasal commensal viruses.

Signal transduction and targeted therapy·2026

Same author

Correlated expression of MYBL2 and CCL5 defines an immunosuppressive microenvironment and predicts poor prognosis in intrahepatic cholangiocarcinoma.

BMC cancer·2026

Search research articles

Related Experiment Video

Updated: Jul 7, 2025

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

Optimized Design of Solid-Liquid Dual-Impeller Mixing Systems for Enhanced Efficiency.

Ding Xia^1,2, Zijian Mao^1,2, Shuiqing Zhou^1,2

¹College of Mechanical Engineering, Zhejiang University of Technology, Hangzhou 310023, China.

|December 25, 2023

Summary

Optimizing dual-impeller stirred tank geometry significantly improves solid-liquid suspension and reduces energy waste. This study enhances mixing efficiency by minimizing flow losses near tank walls and baffles.

More Related Videos

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Published on: May 16, 2018

Related Experiment Videos

Last Updated: Jul 7, 2025

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Published on: September 13, 2018

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

Published on: December 25, 2015

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Published on: May 16, 2018

Area of Science:

Chemical Engineering
Fluid Dynamics
Computational Fluid Dynamics

Background:

Flow interferences in dual-impeller stirred tanks reduce stirring energy efficiency.
Inefficiencies arise from interactions between impellers, baffles, and tank walls.

Purpose of the Study:

To optimize stirred tank geometry for enhanced mixing efficiency and homogeneity.
To reduce energy consumption and cost in solid-liquid mixing processes.

Main Methods:

Euler-Euler numerical simulation and particle image velocimetry (PIV) for flow analysis.
Sobol method for sensitivity analysis to identify key design parameters.
Multiobjective optimal design combining RBF agent model and Sobol method.

Main Results:

Optimized design significantly improved solid-liquid suspension capacity.
Flow losses near walls and baffles were considerably reduced.
Cloud height increased by 8.7%, and power consumption decreased by 15.6%.

Conclusions:

The study successfully enhanced mixing efficiency and homogeneity in solid-liquid stirred tanks.
The multiobjective optimal design approach is validated as feasible and effective.
Findings provide valuable insights for designing efficient mixing equipment.