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Updated: Jul 7, 2025
An Efficient Single—Person Technique for Milk Sampling from Laboratory Mice
Published on: March 28, 2025
Analysis for lipid nutrient differences in the milk of 13 species from a quantitative non-targeted lipidomics
Yanzhi Wu1, Yinggang Sun1, Rui Chen1
1College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
Abstract:
Lipids are essential organic components in milk and have been associated with various health benefits for newborns. However, a comprehensive analysis of lipid profiles across multiple species and levels has been lacking. In this study, we employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to accurately determine the absolute content of lipid molecules. It revealed that ruminants exhibit a higher concentration of short-chain fatty acids compared to non-ruminants. Additionally, we identified ALC (camel), MGH (horse), and DZD (donkey) as species that display similarities to components found in human milk fat. Remarkably, it reveals that porcine milk fat is characterized by long chain lengths, low saturation, and a high proportion of essential fatty acids. PS (22:5_18:2) could potentially serve as a biomarker in porcine milk. These unique characteristics present potential opportunities for the utilization of porcine milk. Overall, our findings provide valuable insights into the lipidomics profiles of milk from different species.
