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Updated: Jul 7, 2025

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Design and Implementation of a Bespoke Robotic Manipulator for Extra-corporeal Ultrasound
Published on: January 7, 2019
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Ultrasound robotics for precision therapy
Alexia Del Campo Fonseca1, Daniel Ahmed1
1Department of Mechanical and Process Engineering, Acoustic Robotics Systems Lab, ETH Zurich, Säumerstrasse 4, 8803 Rüschlikon, Switzerland.
Advanced Drug Delivery Reviews
|December 25, 2023
Summary
Acoustic microrobots offer precise medical therapies by navigating the body. This review explores their principles, applications in drug delivery and tissue targeting, and challenges for clinical use.
Area of Science:
- Biomedical Engineering
- Robotics
- Acoustic Physics
Background:
- Microrobots are gaining traction for precision therapy due to their ability to reach difficult areas.
- Acoustic actuation is a key technology for controlling microrobots, enabling targeted navigation and therapy delivery.
- Challenges remain in translating these miniature agents from research to clinical applications.
Purpose of the Study:
- To review fundamental acoustic principles used in microrobot technology.
- To assess current medical therapy applications of acoustic microrobots, including drug delivery and tissue targeting.
- To discuss ongoing efforts in integrating acoustic microrobots for in vivo use.
Main Methods:
- Review of acoustic principles for microrobot actuation.
- Analysis of current literature on microrobot applications in medical therapies.
- Examination of challenges and advancements in in vivo translation.
Main Results:
- Acoustic principles provide precise control for microrobot navigation and function.
- Applications include targeted drug delivery, tissue infiltration, and precise site-specific therapies.
- Significant hurdles exist in clinical translation, requiring further research and development.
Conclusions:
- Acoustic microrobots show great promise for enhancing precision and effectiveness in medical treatments.
- Further investigation into in vivo integration and overcoming clinical translation barriers is crucial.
- This technology has the potential to revolutionize targeted therapies and reduce side effects.

