Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

5.6K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.6K
Cancer02:18

Cancer

48.5K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
48.5K
Cancer Prevention02:59

Cancer Prevention

6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
6.2K
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

7.4K
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
7.4K
Tumor Immunotherapy01:27

Tumor Immunotherapy

529
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
529
Cancer Survival Analysis01:21

Cancer Survival Analysis

355
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
355

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Announcing a New Article Type in <i>JCO Clinical Cancer Informatics</i>: The Resource Report.

JCO clinical cancer informatics·2026
Same author

Multi-Modal Deep Learning-Based Model to Predict Burkitt Lymphoma Recurrence.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science·2026
Same author

Making LLM Predictions Interpretable: Fine-Tuning GPT-4o for Early Discontinuation of Cancer Medication.

Studies in health technology and informatics·2026
Same author

Twenty-First Century Data Systems: Evolving Cancer Registries to a Learning Health System.

Learning health systems·2026
Same author

Supporting Reimbursement for Electronic Patient-Reported Outcomes in Clinical Cancer Care Using Current Procedural Terminology Codes for Remote Therapeutic Monitoring.

JCO oncology practice·2026
Same author

An agentic AI system enhances clinical detection of immunotherapy toxicities: a multi-phase validation study.

medRxiv : the preprint server for health sciences·2026
Same journal

Citizens' Options When Accessing and Sharing Health Information - An International Survey of IMIA Member Countries.

Yearbook of medical informatics·2025
Same journal

Social Determinants of Health in Digital Health Policies: an International Environmental Scan.

Yearbook of medical informatics·2025
Same journal

Sensors, Signals, and Imaging Informatics: Best contributions from 2023.

Yearbook of medical informatics·2025
Same journal

Alzheimer Disease Detection Studies: Perspective on Multi-Modal Data.

Yearbook of medical informatics·2025
Same journal

Exploring the Latest Advances in Public Health and Epidemiology Informatics.

Yearbook of medical informatics·2025
Same journal

Application of Digital Informatics in Precision Prevention, Epidemiology, and Clinicogenomics Research to Advance Precision Healthcare.

Yearbook of medical informatics·2025
See all related articles

Related Experiment Video

Updated: Jul 7, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
07:41

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

9.0K

Cancer Informatics 2023: Data Sharing and Federating Learning Point Towards New Collaborative Opportunities.

Jeremy L Warner1,2, Debra Patt3,

  • 1Professor, Department of Medicine, Brown University, Providence, RI, USA.

Yearbook of Medical Informatics
|December 26, 2023
PubMed
Summary
This summary is machine-generated.

Cancer informatics research in 2022 highlights advances in federated learning, drug synergy prediction, and clinical note data utilization. These key findings showcase the growing impact of informatics in cancer research and data sharing.

More Related Videos

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

2.5K
Predictive Immune Modeling of Solid Tumors
08:50

Predictive Immune Modeling of Solid Tumors

Published on: February 25, 2020

7.0K

Related Experiment Videos

Last Updated: Jul 7, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
07:41

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

9.0K
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

2.5K
Predictive Immune Modeling of Solid Tumors
08:50

Predictive Immune Modeling of Solid Tumors

Published on: February 25, 2020

7.0K

Area of Science:

  • Biomedical Informatics
  • Cancer Research
  • Data Science

Background:

  • Cancer informatics is a rapidly evolving field.
  • Significant research contributions are published annually.
  • Identifying key advancements is crucial for progress.

Purpose of the Study:

  • To summarize significant research contributions in cancer informatics published in 2022.
  • To highlight key advancements and trends in the field.
  • To identify the top three impactful papers from 2022.

Main Methods:

  • Extensive literature search of PubMed/MEDLINE for 2022 publications.
  • Multi-step selection process involving editors, external reviewers, and editorial board.
  • Identification of candidate best papers and final selection based on rigorous review.

Main Results:

  • Three significant research papers were selected.
  • Advances demonstrated in federated learning for cancer data.
  • Progress shown in drug synergy prediction and clinical note data utilization.

Conclusions:

  • Cancer informatics is maturing as a subfield of biomedical informatics.
  • Informatics methods are increasingly applied to data sharing.
  • Federated approaches show notable promise in cancer research.