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Decreased Risk of Periprosthetic Joint Infection with Concurrent Hardware Removal During Conversion Total Hip
Sean B Sequeira1, Mark D Hasenauer, Robert McKinstry
1From the Department of Orthopaedic Surgery, MedStar Union Memorial Hospital, Baltimore, MD.
Insights
Hardware removal before hip replacement surgery increases the risk of periprosthetic joint infection (PJI). However, the timing of hardware removal does not impact revision surgery, fracture, or loosening rates.
Area of Science:
- Orthopaedic Surgery
- Biomedical Engineering
- Clinical Outcomes Research
Background:
- Hardware removal prior to conversion total hip arthroplasty (cTHA) presents surgical challenges.
- Optimal timing for hardware removal to minimize complications post-cTHA remains unclear.
Purpose of the Study:
- To evaluate the impact of hardware removal timing on complications following cTHA.
- To compare the risks of revision surgery, periprosthetic joint infection (PJI), periprosthetic fracture, and aseptic loosening between concurrent and staged hardware removal.
Main Methods:
- A national insurance database was used to identify 7,756 patients undergoing hardware removal and cTHA.
- Patients were divided into concurrent (same-day) and staged (within 1 year prior) hardware removal groups.
- Matched cohorts of 2,752 patients each were analyzed for 90-day and 1-year complication rates.
Main Results:
- The staged cohort showed significantly higher rates of PJI at 90 days (3.05% vs 1.85%) and 1 year (4.14% vs 2.94%) compared to the concurrent cohort.
- No significant differences were found in the rates of fracture, revision surgery, or aseptic loosening between the groups.
- Diabetes, tobacco use, and obesity were identified as risk factors for PJI.
Conclusions:
- Staged hardware removal prior to cTHA is associated with an increased risk of PJI.
- The timing of hardware removal does not appear to affect the risk of revision surgery, fracture, or loosening.
- Surgeons should consider these findings when managing patients with periarticular implants requiring cTHA.
Introduction:
Hardware removal before conversion total hip arthroplasty (cTHA) is a challenging task for the orthopaedic surgeon, although there is little consensus on the timing of hardware removal to mitigate risk of surgery-related complication following cTHA.
Methods:
Using a national insurance database, we evaluated patients who underwent hardware removal either on the same day or within 1 year before cTHA, resulting in a total of 7,756 patients. After matching based on demographic factors and comorbidities, both staged and concurrent groups consisted of 2,752 patients. The 90-day and 1-year risk of revision surgery, periprosthetic joint infection (PJI), periprosthetic fracture, and aseptic loosening were calculated and compared. Demographic factors and comorbidities were further evaluated as risk factors for PJI.
Results:
The rates of infection were 1.85% and 3.05% at 90 days postoperatively and 2.94% and 4.14% at 1 year postoperatively for concurrent versus staged cohorts, respectively (P = 0.004 and P = 0.02). No difference was observed at 90 days or 1 year between the two cohorts in risk of fracture, revision surgery, or aseptic loosening. Diabetes (P = 0.002 and P < 0.001), tobacco use (P < 0.001 and P < 0.001), and obesity (P = 0.026 and P = 0.025) were identified as risk factors for PJI at both 90 days and 1 year postoperatively.
Discussion:
The timing of hardware removal is associated with an increased risk of PJI, although no difference was observed in revision surgery, fracture, or loosening among staged versus concurrent cohorts. These findings are important to consider when surgeons are evaluating patients with periarticular implants surrounding their hip.
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