Related Experiment Video
Updated: Jul 7, 2025
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
39.0K
[Recommendations for psoriasis treatment in Pediatrics]
Paula Carolina Luna1, María Eugenia Abad2, Margarita Larralde3
1Hospital Alemán, Buenos Aires. recomendaciones_psoriasis@hotmail.com.
Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|December 27, 2023
Summary
This guideline provides evidence-based recommendations for the systemic treatment of pediatric psoriasis, emphasizing physician-patient collaboration for optimal outcomes in children and adolescents.
Area of Science:
- Dermatology
- Pediatrics
- Evidence-Based Medicine
Context:
- Psoriasis affects one-third of patients during childhood and adolescence, significantly impacting psychosocial well-being.
- Developing specific guidelines for pediatric psoriasis treatment is crucial due to its unique challenges and long-term effects.
Purpose:
- To establish a guideline for the systemic treatment of psoriasis in pediatric patients.
- To provide evidence-based recommendations for managing childhood and adolescent psoriasis.
Summary:
- A comprehensive literature search identified relevant studies published between 2010 and 2022.
- The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was used to evaluate evidence quality and formulate recommendations.
- Eight recommendations and seven good practice points were developed for pediatric psoriasis systemic treatment.
Impact:
- The guideline aims to improve the quality of care for pediatric psoriasis patients.
- It supports clinical decision-making by providing structured, evidence-based treatment options.
- Emphasizes personalized treatment plans considering patient values and physician expertise.
More Related Videos
Related Concept Videos
01:22iPS Cell Differentiation
2.7K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.7K
01:30Skin Cancer
4.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.1K
01:29Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
166
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
166
01:21Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
120
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
120
01:29Inflammatory Bowel Disease IV: Pharmacological Management
128
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
128
01:19Clinical Applications of Epidermal Stem Cells
2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K