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A Remotely Delivered, Semaglutide-Supported Specialist Weight Management Program: Preliminary Findings From a
Rebecca Richards1, Gina M Wren2, Peta Campion1
1Second Nature, London, United Kingdom.
JMIR Formative Research
|December 28, 2023
Summary
This study shows a remotely delivered weight management program using semaglutide is effective for adults with obesity, with significant weight loss in 12 weeks. Further research is needed to improve user engagement.
Area of Science:
- Obesity management
- Digital health interventions
- Pharmacotherapy
Background:
- Digital interventions can improve access to obesity pharmacotherapy.
- Limited real-world data exists on these interventions' effectiveness, feasibility, and acceptability.
Purpose of the Study:
- To evaluate the preliminary impact of a 24-month, remotely delivered, semaglutide-supported weight management intervention for adults with obesity at 12 weeks.
Main Methods:
- Retrospective data analysis of 113 participants over 12 weeks.
- Primary outcomes: weight change (kg) and percentage.
- Secondary outcomes: achievement of ≥5% and ≥10% weight loss, feasibility, and acceptability.
Main Results:
- Average weight loss of 6.5 kg (6.4%) (P<.001).
- 62.5% achieved ≥5% weight loss; 11.3% achieved ≥10% weight loss.
- High acceptability reported, though app engagement declined and some experienced side effects or logistical issues.
Conclusions:
- Remotely delivered semaglutide-supported weight management shows potential effectiveness, feasibility, and acceptability for adults with obesity.
- Improvements in app engagement and logistics are recommended.
- Further evaluation with a larger sample size at 24 months is warranted.
