Regional distribution of metals in human brain

Progress in understanding the role of metals in diseases of the nervous system has been hampered to a large extent by a lack of normal metal concentration values in the human brain. Since several metals interact metabolically, concurrent metal levels are essential for clinical correlation. We are reporting a simultaneous analysis of 24 metals in 4 different areas of 9 human brains. Our data on previously studied metals are comparable to the past observations. Therefore, we suggest the values of all metals reported here should be regarded as "normal" for ages 58-78 years.