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Hydrolytic nanozymes: Preparation, properties, and applications
Tianyou Chen1, Yizhuo Lu1, Xiaorong Xiong1
1Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University, Wuhan 430062, China.
Advances in Colloid and Interface Science
|December 30, 2023
Summary
Hydrolytic nanozymes offer stable, cost-effective alternatives to natural enzymes for hydrolysis reactions. This review covers their preparation, properties, and applications in areas like synthesis and sensing.
Area of Science:
- Catalysis and Nanotechnology
Background:
- Hydrolytic enzymes face limitations in operating conditions.
- Nanozymes provide stable, tunable, and cost-effective alternatives for hydrolysis.
Purpose of the Study:
- To review the preparation, properties, and applications of various hydrolytic nanozymes.
- To highlight recent advancements and future directions in hydrolytic nanozyme development.
Main Methods:
- Review of literature on six types of hydrolytic nanozymes: AuNP-based, polymeric, surfactant assemblies, peptide assemblies, metal/metal oxide nanoparticles, and MOFs.
- Analysis of their preparation methods, catalytic properties, and application potential.
Main Results:
- Nanozymes exhibit superior operating stability, reusability, and adjustable catalytic properties compared to natural enzymes.
- Diverse nanozyme types (AuNP, polymeric, etc.) demonstrate efficacy in organic synthesis, chemical weapon degradation, and biosensing.
Conclusions:
- Hydrolytic nanozymes are versatile and promising for various applications, overcoming limitations of natural enzymes.
- Further research is needed to address challenges and fully exploit the potential of hydrolytic nanozymes.

