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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
415
Association between psoriasis and dementia: A systematic review.
1Academy of Life Sciences, School of Medicine, Xi'an International University, Xi'an, China.
Neurologia
|December 31, 2023
Summary
Psoriasis, a chronic inflammatory disease, may increase dementia risk. Most studies reviewed suggest a link, but further research is needed to confirm this association.
Area of Science:
- Dermatology and Neurology
- Systemic Inflammatory Diseases
Background:
- Dementia risk factors include genetics, aging, environment, diseases, and lifestyle.
- Psoriasis is a chronic systemic inflammatory disease.
- A potential link between psoriasis and increased dementia risk is under investigation.
Approach:
- Systematic literature review following PRISMA guidelines.
- Searched PubMed and Web of Science for studies on psoriasis and dementia.
- Assessed study quality using the Newcastle-Ottawa Scale; 8 studies were included.
Key Points:
- Six of eight reviewed studies supported the hypothesis that psoriasis increases dementia risk.
- One study indicated a decreased risk, while another found no significant association.
- Three studies had a higher risk of bias.
Conclusions:
- Most evidence suggests psoriasis is a risk factor for dementia.
- Further high-quality, stratified cohort studies are necessary.
- Investigating psoriasis severity and treatment impact on dementia risk is crucial.
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