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Related Concept Videos

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
662
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

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The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
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Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
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Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Schizophrenia01:17

Schizophrenia

86
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
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Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

91
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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Related Experiment Video

Updated: Jul 6, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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COVID-19 associated psychosis.

Antonino Messina1, Maria Salvina Signorelli1

  • 1Department of Clinical and Experimental Medicine, Institute of Psychiatry, University of Catania, Catania, Italy.

Industrial Psychiatry Journal
|January 1, 2024
PubMed
Summary

Cases of psychosis, including delusions and hallucinations, have been reported during and after COVID-19. While a causal link is unproven, the SARS-CoV-2 virus

Keywords:
COVID-19SARS-CoV-2delusiondisorganizationhallucinationparanoiapsychosispsychotic disorders

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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
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Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Psychiatry

Background:

  • The COVID-19 pandemic has been associated with reported cases of psychosis, including delusions, hallucinations, and disorganized behavior.
  • These symptoms have been observed during both acute infection and post-recovery phases of COVID-19.
  • While a direct causal link between COVID-19 and psychotic disorders is still under investigation, emerging data warrants attention.

Purpose of the Study:

  • To review existing literature on the association between COVID-19 and psychotic disorders.
  • To explore the potential neurological mechanisms linking SARS-CoV-2 to psychosis.
  • To propose criteria for identifying potential cases of COVID-19-related psychosis.

Main Methods:

  • Systematic review of published case reports and reviews analyzing the link between COVID-19 and psychotic disorders.
  • Analysis of scientific findings regarding SARS-CoV-2's ability to cross the blood-brain barrier and affect neurons.
  • Development of proposed study criteria for COVID-19-related psychosis.

Main Results:

  • A growing body of literature suggests a correlation between COVID-19 infection and the onset of psychotic symptoms.
  • Evidence indicates that SARS-CoV-2 can penetrate the blood-brain barrier and neurons, providing a potential biological pathway.
  • The review highlights the need for further research to understand this complex relationship.

Conclusions:

  • The observed association between COVID-19 and psychosis necessitates further investigation.
  • Proposed criteria aim to aid in the identification and study of potential COVID-19-related psychosis.
  • Continued research is crucial to elucidate the etiological mechanisms and clinical implications.