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Ureteric Leiomyosarcoma.

Anupama Bahadur1, Rajlaxmi Mundhra1, Anoosha K Ravi1

  • 1Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Cureus
|January 1, 2024
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Summary

Ureteric leiomyosarcoma, a rare aggressive tumor, typically presents as abdominal pain in women over 40. This case highlights a younger patient and the importance of histopathology for diagnosis and treatment.

Keywords:
adnexal massleiomyosarcomasarcomaspindle cell tumorureter

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Area of Science:

  • Oncology
  • Uropathology

Background:

  • Ureteric leiomyosarcoma is an exceptionally rare and aggressive smooth muscle tumor arising from the ureter.
  • Limited epidemiological data exists due to its rarity, with existing literature primarily consisting of case reports.

Observation:

  • The case involved a 32-year-old female presenting with symptoms initially suspected as an adnexal mass.
  • Intraoperative findings revealed a left ureteric tumor, with ovaries appearing normal.
  • Diagnosis was confirmed via histopathological examination and immunohistochemistry.

Findings:

  • The tumor was surgically managed through excision, partial ureteric resection, and end-to-end anastomosis.
  • Post-operative treatment included chemotherapy and radiation therapy.

Implications:

  • This case expands the known age range for ureteric leiomyosarcoma presentation.
  • It underscores the diagnostic challenge and the necessity of a multidisciplinary approach for rare genitourinary sarcomas.
  • Highlights the role of surgical intervention combined with adjuvant therapies in managing this aggressive malignancy.