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Arginine: A New Paradigm in Preventive Oral Care
Varinder Goyal1, Satyawan Damle2, Manjunath P Puranik3
1Department of Pediatric and Preventive Dentistry, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India.
International Journal of Clinical Pediatric Dentistry
|January 1, 2024
Summary
Arginine, an amino acid, enhances fluoride's cavity prevention by promoting a healthy oral microbiome. Combining arginine with fluoride in toothpaste offers improved dental caries protection.
Area of Science:
- Biochemistry
- Oral Health
- Preventive Dentistry
Background:
- Dental caries is a widespread oral disease impacting quality of life.
- Fluoride is effective but has limitations in caries prevention.
- Arginine supports a noncariogenic oral plaque environment.
Purpose of the Study:
- To investigate the synergistic effects of arginine and fluoride in preventing dental caries.
- To highlight the benefits of arginine supplementation in oral care formulations.
- To provide guidance on the combined use of arginine and fluoride for effective caries prevention.
Main Methods:
- Review of clinical studies evaluating 1.5% arginine with fluoride in dentifrices.
- Analysis of arginine's role in maintaining oral health and remineralization.
- Synthesis of evidence supporting arginine-fluoride synergy.
Main Results:
- Arginine demonstrates synergistic effects with fluoride in combating dental caries.
- Arginine enhances tooth remineralization, complementing fluoride's action.
- Clinical evidence supports the efficacy of arginine-fluoride combinations.
Conclusions:
- Supplementing fluoride dentifrices with arginine can significantly improve caries prevention.
- Arginine offers a novel approach to enhance oral care and reduce caries incidence.
- Recommendations are provided for the effective integration of arginine in preventive dental strategies.
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