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Related Concept Videos

The Cochlea01:13

The Cochlea

45.0K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
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Hair Cells01:22

Hair Cells

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Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
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Equilibrium and Balance01:15

Equilibrium and Balance

4.7K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
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Related Experiment Video

Updated: Jul 6, 2025

Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
09:35

Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis

Published on: July 18, 2011

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Rate Dependent Cochlear Outer Hair Cell Force Generation: Models and Parameter Estimation.

Wen Cai, Karl Grosh

    Biorxiv : the Preprint Server for Biology
    |January 3, 2024
    PubMed
    Summary
    This summary is machine-generated.

    Outer hair cells (OHCs) use prestin to convert electrical to mechanical energy for sensitive hearing. Our model clarifies prestin

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    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells
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    Related Experiment Videos

    Last Updated: Jul 6, 2025

    Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
    09:35

    Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis

    Published on: July 18, 2011

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    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats
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    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats

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    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells
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    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells

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    Area of Science:

    • Auditory Neuroscience
    • Biophysics
    • Mechanobiology

    Background:

    • Outer hair cells (OHCs) are crucial for sensitive, frequency-specific hearing in mammals.
    • The membrane protein prestin is hypothesized to provide OHCs with piezoelectric-like properties for electromechanical transduction.
    • This mechanism is vital for amplifying cochlear responses to low-level sounds, but key aspects remain debated.

    Conclusions:

    • Rate dependence and viscoelasticity significantly influence OHC electromechanical force generation.
    • Accurate estimation of OHC properties requires careful consideration of mechanical boundary conditions.
    • The study provides a theoretical and experimental basis for further research into hearing mechanisms.