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Cell Adhesion in Plants

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Related Experiment Video

Updated: Jul 6, 2025

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

Progress of polysaccharide-based tissue adhesives.

Gi-Yeon Han¹, Ho-Wook Kwack¹, Yo-Han Kim²

¹Program in Environmental Materials Science, Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul 08826, Republic of Korea.

Carbohydrate Polymers

|January 3, 2024

Summary

Polysaccharide-based tissue adhesives offer a promising alternative to sutures for wound closure. This review explores their properties, mechanisms, and future potential for improved medical applications.

Keywords:

Natural polymer Next-generation Polysaccharide Tissue adhesive

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Published on: August 19, 2015

Area of Science:

Biomaterials Science
Polymer Chemistry
Surgical Innovation

Background:

Polymer-based tissue adhesives (TAs) are emerging as alternatives to sutures due to ease of use and minimal tissue damage.
Current TAs face limitations in mechanical properties and adhesion strength, necessitating advanced solutions.
Next-generation TAs with enhanced multifunctional properties are crucial for broader clinical adoption.

Purpose of the Study:

To review the requirements for polymeric tissue adhesives.
To comprehensively analyze polysaccharide (PS)-based TAs, including chitosan (CS), alginate (AL), dextran (DE), and hyaluronic acid (HA).
To discuss adhesive characteristics, strength assessment, mechanisms, applications, and commercial products.

Main Methods:

Literature review of polysaccharide-based tissue adhesives.
Analysis of adhesive properties, mechanical performance, and biological interactions.
Evaluation of current and potential applications in wound closure and sealing.

Main Results:

Polysaccharide-based TAs demonstrate potential for improved adhesion and mechanical strength.
Various polysaccharides offer distinct advantages for specific tissue adhesion applications.
Understanding adhesion mechanisms is key to optimizing TA performance.

Conclusions:

Polysaccharide-based tissue adhesives represent a significant advancement in wound closure technology.
Further research into multifunctional properties will enhance their clinical utility.
Future perspectives highlight the potential for innovative biomaterial development in TAs.