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Improving medication adherence in cardiovascular disease.
Adam J Nelson1,2, Neha J Pagidipati2, Hayden B Bosworth3,4
1Victorian Heart Institute, Melbourne, Victoria, Australia.
Nature Reviews. Cardiology
|January 3, 2024
Summary
Medication non-adherence is a significant global health issue, especially for cardiovascular disease patients. This review identifies causes and effective interventions to improve medication adherence.
Area of Science:
- Cardiology
- Public Health
- Pharmacology
Background:
- Medication non-adherence presents substantial individual and population health challenges, often overlooked in clinical practice.
- The prevalence of cardiovascular disease and medication non-adherence is projected to rise due to aging populations and increased comorbidity.
- Current methods for detecting non-adherence are imperfect, with no established gold standard despite technological advancements.
Purpose of the Study:
- To identify the multifaceted causes of medication non-adherence.
- To review interventions proven effective in randomized clinical trials for improving adherence.
- To propose practical solutions and future research directions for medication non-adherence.
Main Methods:
- Literature review of causes of medication non-adherence.
- Systematic summary of interventions demonstrated effective in randomized clinical trials.
- Analysis of current detection methods and technological limitations.
Main Results:
- Non-adherence is dynamic, influenced by multiple factors, particularly in chronic conditions like cardiovascular disease requiring lifelong management.
- Various interventions have shown efficacy in improving adherence through rigorous clinical trials.
- The review highlights the need for improved detection and tailored interventions.
Conclusions:
- Addressing medication non-adherence requires a comprehensive understanding of its causes and the implementation of evidence-based interventions.
- Future research should focus on developing more accurate detection methods and personalized adherence strategies.
- Clinical settings must prioritize and better address medication non-adherence for improved patient outcomes.
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